Investigating the Cancer and Aging Link
through Systems Biology (CALSYS)
Institute for Biostatistics and Informatics
in Medicine and Ageing Research, Rostock
invite you cordially to the
RoSyBA: Rostock Symposium on Systems Biology and Bioinformatics in Ageing Research
15th-17th September 2011
The workshop is kindly sponsored by the BMBF, the SENS Foundation, Sanofi-Aventis and by the Department of
Medicine and the Department of Aging Science and Humanities (Interdisz. FakultŠt), Univ. Rostock.
Registration is still possible on site. Fees: 300Û for Academia/Industry, 200Û for Graduate Student/Trainee.
Day Tickets: Thu: 50%, Fri: 70%, Sat: 30% of the fee as above.
Aims and Topics
In an Òageing societyÓ, healthspan extension is most important. As in 2010 (Rejuvenation Res. 13:763-7), talks in this meeting demonstrate that ageing is a complex process, where in-silico work can be most useful to gain insight, and to find interventions. Specific topics of this yearÕs meeting are ÒCancer and AgeingÓ, and a focus on work funded by the German ministry (BMBF).
Thursday 15.09.2011 (Kurhaus WarnemŸnde)
Chair: Georg Fuellen, Julio Vera
16:10-17:00 Stuart Kim, Stanford University, USA: "Genome-wide views of ageing gene networks"
17:00-17:30 Andreas Hšflich, Leibniz Institute, Dummerstorf, Germany: "Interactions between growth, metabolism and aging"
17:30-17:50 Daniel Wuttke, University of Liverpool, UK: ÒComparative Interactomics of DR-Essential GenesÓ (talk rescheduled)
Chair: Stuart Kim
18:10-18:40 Pat Langley, Arizona State University: "Computational Support for Systems Biology of Aging" (speaker changed, talk rescheduled, via Internet)
18:40-19:05 Niels Grabe, University of Heidelberg "From in vitro models to networks: approaches for studying aging skin"
19:05-19:20 Attila Altiner, University Rostock: ÒÕSuccessful AgeingÕ in the year 2025: Dreams and nightmares of a General PractitionerÓ
Friday 16.09.2011 (Kurhaus WarnemŸnde)
9:20- 9:30 Announcements
Chair: Anne Brunet
9:30-10:15 Jan Hoeijmakers, Erasmus University, Rotterdam, Netherlands: ÒThe Genome Maintenance: Impact on Aging and DiseaseÓ
10:15-10:45 Manuel Collado, Spanish National Cancer Research Centre (CNIO), Madrid, Spain: "Impact of tumour suppressors on aging" (speaker changed)
10:45-11:05 Kristen Fortney, University of Toronto, Canada: ÒMining genome-wide drug-response compendia to discover novel calorie restriction mimeticsÓ
Chair: GŸnter Lepperdinger
11:30-12:15 Anne Brunet, Stanford, USA: ÒNeural stem cells and aging"
12:15-12:35 Ana Vi–uela, KingÕs College London, UK: ÒGenome-wide transcriptome analysis with age and the effect of natural genetic variation in humansÓ
12:35-12:55 Aurel Popa-Wagner, University of Greifswald, Germany: ÒIdentification of new therapeutics targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after strokeÒ
12:55-13:15 Adolf E. Schindler, University of Essen, Germany: ÒIsoflavones and breast cancerÓ
Chair: Manuel Collado
14:30-15:15 GŸnter Lepperdinger, Institute for Biomedical Aging Research, Innsbruck, Austria: ÒHomeodynamic fitness - age-related dysbalance in mesenchymal stem cell
renewal and progenitor moldingÓ
15:15-15:45 Alexandra Stolzing, Fraunhofer Inst. Cell Therapy and Immunology, Leipzig, Germany: ÒInto the deep: signal pathway analysis in aged MSCÓ (talk rescheduled)
15:45-16:05 Katrin Zeilinger, Charite, Berlin, Germany: ÒOXISYS - Role of oxidative injury in aging and therapeutic implicationsÓ (talk rescheduled)
16:30-16:50 Brief Business Meeting: Submission of Meeting Report, RoSyBA 2012/2013, Stem Cell Ageing
Chair: Jan Hoeijmakers
16:50-17:10 Joern Dengjel, University Hospital Freiburg, Germany: "Omics Analysis to pave the Road of Systems Biology in Kidney Aging"
17:10-17:30 Claudia Gey, University of Luebeck, Germany: "Oxygen signaling and metabolism in a cell model of oncogene-induced senescence"
17:30-17:50 Fiete Haack, University of Rostock, Germany: "The role of Lipid Rafts in Aging and Cellular Senescence"
17:50-18:10 Ulf Schmitz, University of Rostock, Germany: "Integrating Bioinformatics and Systems Biology to elucidate the role of miRNAs in cancer and aging"
18:10-18:30 Bernd Schmeck, Charite, Berlin: "Systems Biology of Inflammation in Ageing" (talk rescheduled)
19:30-21:30 Boat Trip -- registered participants (boat leaving close to the main train station and close to the ferry to "Hohe Duene", see map)
Saturday 17.09.2011 (Institut fuer Physiologie)
8:25- 9:00 Free transfer from Hotel Neptun (just opposite of Kurhaus WarnemŸnde) to Institut fuer Physiologie – registered participants – please inquire at registration desk – dept. 8:25 on time!
9:10- 9:15 Announcements
Chair: Thomas von Zglinicki
9:15-10:00 Joao Pedro de Magalhaes, University of Liverpool, UK: ÒBuilding haystacks and finding needles in the genomics of ageingÓ
10:00-10:25 Steffen Priebe, HKI, Jena: "RNA-Seq data analysis to study aging within a multi-species approach"
10:25-10:50 Stefan Schuster, Univ. Jena: "Metabolic Pathway Analysis of NAD+ metabolism with special reference to age research"
11:10-11:35 Bianca Habermann, Max Planck Institute for Biology of Ageing, Cologne: "Finding cross-links and mechanistic links in biological networks"
11:35-12:00 Axel Kowald, Humboldt University, Berlin: "Modelling the effects of SOD overexpression on ROS metabolism and protein quality control"
Chair: Joao Pedro de Magalhaes
13:00-13:45 Thomas von Zglinicki, University of Newcastle, UK: "Mitochondrial dysfunction in cell senescence"
13:45-14:10 Jšrg Galle, University of Leipzig: ÒModeling the Ageing EpigenomeÓ
14:10-14:35 JŸrgen SŸhnel, Leibniz Institute for Ageing Research, Jena ÒData and Information Processing for Age ResearchÓ
14:55-15:20 Saleh Ibrahim / Georg Fuellen, University of LŸbeck / Rostock ÒMitochodrial genome and aging: a systems biology approachÓ
15:20-15:45 Hans Kestler, University of Ulm ÒBoolean networks and their evolution for modeling gene regulationÓ
16:05-16:10 Free transfer from Institut fuer Physiologie to main train station – registered participants – please inquire at registration desk – dept. 16:05 on time!
Dr. Julio Vera
Systems Biology and Bioinformatics
Ulmenstrasse 69 (building 3, 3rd floor)
18057 Rostock, Germany
+49 381 498-7681
+49 381 498-7572
Prof. Dr. Georg Fuellen
Director, Institute for Biostatistics and Informatics in Medicine and Ageing Research -- IBIMA
(formerly IMIB -- Institute for Medical Informatics and Biometry)
University of Rostock, Medical Faculty
18057 Rostock, Germany
Phone + 49 381 494-7360
Fax + 49 381 494-7203