Institute for Biostatistics and Informatics
in Medicine and Ageing Research, Rostock


RoSyBA: Rostock Symposium on Systems Biology
and Bioinformatics in Ageing Research
20th – 21st September 2013


Thursday 19th September, Informal Get-Together: Hotel Neptun, Rostock/Warnemünde
Friday 20th September: Hotel Neptun, Rostock/Warnemünde
Friday 20th September, Evening Event: Hohe Duene, Rostock/Warnemünde
Saturday 21st September: Institute for Physiology, Rostock
Sunday 22nd September, Brunch: Hotel Neptun, Rostock/Warnemünde


Registration Fees:
After September 5, 2013: 260 EUR for Academia/Industry, 130 EUR for Graduate Student/Trainee.
Friday or Saturday Day Tickets: 60% of the fee listed above.
Sunday Brunch Ticket: 30 EUR flat.
To Register, send email to ibima-events@med.uni-rostock.de, including:
1) Your full name and affiliation,
2) Your status (Academia/Industry/Student),
3) Whether you would like to participate Friday () Saturday () Sunday ().
Expect a response (including details on payment) within a few days maximum.
Note that registration is completed once your payment has been received.

Aims and Topics

The meeting will be a follow-up on the 2011 Rejuvenation Research 2012[pdf] and 2010 (Rejuvenation Research 2010 [pdf]) meetings, with a focus on ontologies (on Friday 9:15-14:10.)

After the symposium, there will be a Sunday Brunch on Meta-Issues of Ageing Research, on 22nd September 2013, 10-13h, see also below.
Before the Symposium, Thursday 19th September 2013 at 17h, Barry Smith (Buffalo, USA) will give a talk (in German), entitled 'e-Menschen: Wie neue Informationstechnologien unser Leben verändern werden' (Ulmenstrasse 69, Hörsaal 1).

Final Program

(Updated: Abstracts Book, Version 0.3, 18.9.13)

Thursday Evening: Informal Get-Together (starting 19:30h), self-pay. Venue: Hotel Neptun, Rostock/Warnemünde. A table has been reserved in the Bistro NEPTUN's M.

Friday (Venue: Hotel Neptun, Rostock/Warnemünde)

 9:00- 9:05  Welcome adresses
 9:05- 9:50  Barry Smith, University of Buffalo: What is Ageing?
 9:50-10:15  Dietrich Rebholz-Schuhmann, University of Zurich: Semantic normalisation of phenotypes: state of the art and prospects  


10:35-11:20  Udo Hahn, University of Jena: Biomedical Natural Language Processing for Aging Research
11:20-11:50  Daniel Wuttke, Anton Kaluga, University of Liverpool: Web Intelligence to Solve Aging


12:50-13:35  Paul Schofield, University of Cambridge: Applying phenotype ontologies to high throughput ageing studies in the mouse; genotype/phenotype associations and new insights into the pathology of ageing
13:35-14:25  Panel discussion on Ontologies for Ageing Research

14:25-14:50  Anne Meinema, Georges Janssens, University of Groningen: Molecular system-level phenotyping to unravel causes in yeast ageing


15:10-15:40  Melanie Boerries, Hauke Busch, University of Freiburg: An "Omics" View on Kidney Aging
15:40-16:05  Fritz Boege, University of Düsseldorf: Ingrained phenotype changes of dermal fibroblasts from human donors aged 20-70
16:05-16:30  Wolfgang Wagner, University of Aachen: Age-Associated DNA-Methylation Changes are Reversed in Pluripotent Stem Cells
16:30-16:55  Andreas Höflich, FBN Dummerstorf: Reproductive development and aging
16:55-17:05  Attila Altiner, University of Rostock: Could bioinformatics help to reduce polypharmacy in the elderly?

17:20 Meeting Point: Hotel Neptun, Entrance Area: Joint Walk to the Marine Science Center, first group.
17:30 (sharp!) Meeting Point: Hotel Neptun, Entrance Area: Joint Walk to the Marine Science Center, second and last group.

Friday Evening Event (Venue: Hohe Duehne, Rostock/Warnemünde)

18:15-19:30  Marine Science Center, next to Hohe Duehne: Science Live (registration will be required, at no extra cost)
19:30-22:00  Evening Event (registration will be required, at no extra cost)

Saturday (Venue: Institute for Physiology, Rostock)

 8:50- 9:00  Welcome
 9:00- 9:45  Joao Pedro de Magalhaes, University of Liverpool, UK: Integrative genomics of ageing: New approaches for an "old" problem
 9:45-10:10  Hans Kestler, University of Ulm: Cross-platform and inter-species integration of aging data
10:10-10:35  Jörg Galle, University Leipzig: Understanding epigenetic changes in ageing stem cells - a computational model approach


10:55-11:20  Bianca Habermann, Max Planck Institute for Biology of Ageing, Cologne: Focus Networks for the Integration of Large-scale Data
11:20-11:45  Jürgen Sühnel, Leibniz Institute for Ageing Research, Jena: Towards Data Integration in Age Research  


12:45-13:30  Andreas Simm, University of Halle: Protein glycation in biological aging: a double-edged sword
13:30-13:55  Eva C. Wönne, Thomas Hiller, Charite Berlin: Response of primary human hepatocytes to ethanol exposition in consideration of cellular ageing and oxidative stress in a miniaturized three-dimensional (3D) multicompartment bioreactor system
13:55-14:35  Rüdiger Köhling, Saleh Ibrahim, Georg Fuellen, Johannes Wollbold, University of Lübeck / Rostock: Mouse Mitochondria and Ageing: An Update of ROSAge


14:55-15:20  Christoph Kaleta, Sascha Schäuble, University of Jena: Integrative Data Analysis in Age Research: From differential equations to constraint-based models  
15:20-15:45  Aubrey de Grey, SENS Research Foundation: Organising knowledge about aging for efficient identification of promising intervention strategies

16:00 5-Minute-Bus-Transfer to Main Train Station (Registration Required; Last train leaving to Mid / Southern Germany: 16:25h)

Sunday (Venue: Hotel Neptun, Rostock/Warnemünde)

10:00-13:00 Sunday Brunch on Meta-Issues of Ageing Research
There will be short talks by Aubrey de Grey (on the definition of ageing), by Joao Pedro de Magalhaes, and by Martin Haufschild.


Please email the organizers (ibima-events@med.uni-rostock.de) if you would like to sponsor this event! Current sponsors (as of March 2013):

INF-logoFaculty of Interdisciplinary Research, Rostock University (Department Ageing of individuals and society)

DFG-logo DFG-Project GoodOD (Good Ontology Design)

SENS-logo SENS Research Foundation

BMBF-logo BMBF GerontyoSys-Project ROSAge (Reactive Oxygen Species and the Dynamics of Ageing. A Mitochondrial Multi-gene, Multi-organ Approach)


Prof. Dr. Georg Fuellen
Institute for Biostatistics and Informatics in Medicine and Ageing Research – IBIMA
University of Rostock, Medical Faculty
Ernst-Heydemann-Str. 8
18057 Rostock, Germany
Phone +49 381 494-7360
Fax +49 381 494-7203

PD Dr. Ludger Jansen
Universität Rostock, Institut für Philosophie
August-Bebel-Straße 28, 18051 Rostock
Phone +49 381 498-2811

Dr. Julio Vera
Systems Biology and Bioinformatics
Ulmenstrasse 69 (building 3, 3rd floor, room 402)
18057 Rostock, Germany
+49 381 498-7681
+49 381 498-7572